Publications

Posters

Adherence

Brook RA, Kleinman NL, Wingenbach D, Bron MS, Baran RW. Medication Adherence and the Direct Medical and Prescription Cost Impact of Fixed vs Loose Dose Thiazolidinedione Combination Products Among Type 2 Diabetes Patients. Presented at the Academy of Managed Care Pharmacy 20th Annual Meeting & Showcase, San Francisco, CA, Moscone West Convention Center, April 16-19, 2008. J Manag Care Pharm. Mar 2008;14(2):235-236
Brook RA, Rajagopalan K, Kleinman NL, Beren IA. Medication adherence with Disease modifying treatments for multiple sclerosis: Findings from a US National database of employees. Value Health 2009;13:A371
Fuldeore MJ, Brook RA, Smeeding JE, Dabbous OH. Persistence with Leuprolide Acetate in patients with Prostate Cancer Value Health May 2008:11(3):A73

Asthma

Kleinman NL, Brook RA, Ramachandran S, Wagner S. Pediatric Asthma: An Employer Perspective on Annual Employee and Dependent Costs for Medical Care and Prescription Drugs Value Health May 2008:11(3):A273. May 6, 2008

Biosimilar Drugs

Brook RA, Smeeding JE, Carlisle JA.  The Management of Specialty Drugs, Specialty Pharmacies and Biosimilar Drugs in the United States. Value Health2017;20(5):A26     Click    For Poster   For Abstract

Bipolar Disorder

Brook RA, Rajagoplan K, Hassan M, Young J, Smeeding J, Pikalov. Annual Direct and Indirect Costs of Employees with Bipolar Disorders, Schizophrenia, and Controls from 2001 to 2011. Academy Health. 2013 Annual Research Meeting Poster Presentations, p876-877. Poster C#1254     Click   For Poster.     For Abstract
Brook RA, Rajagopalan K, Kleinman N, Hassan M, Young J, Pikalov A. Annual Direct and Indirect Costs of US Employees with Bipolar Disorders, Schizophrenia and Controls from 2001 to 2011. 2013 Annual Meeting New Research Abstracts, Available at www.psych.org    For Poster
Brook RA, Novak S, Kleinman N, Rajagopalan K, Gardner H, Smeeding JE. Annual Total Medical Costs For Bipolar Disorder Patients Treated With Antipsychotics J Manag Care Pharm. 2006. Mar;12(2):174-175 April 7, 2006. .
Kleinman NL, Rajagopalan K, Brook RA, Novak S, Smeeding JE, Gardner HH. Changes in Mental Health-Related Insurance Claims Costs Among Patients Treated for Bipolar Disorder 2006 Annual Meeting New Research Abstracts p 337 May 24, 2006
Brook RA, Rajagopalan K, Kleinman NL, Hassan M, Young JW, Smeeding JE, Pikalov A. Direct and Indirect Costs Among US Employees with and without Bipolar Disorder or Schizophrenia: Annual Cost Trends from 2001 to 2011. Value Health. 2013 May;16(3): A59
Rajagopalan K, Kleinman N, Brook R, Cape A, Loebel A. Factors Predicting the Likelihood of Lurasidone Initiation in a US Employer Database. 2013 Annual Meeting New Research Abstracts, Available at www.psych.org
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Kleinman N, Brook RA, Gardner H, Rajagopalan K, and Smeeding JE. Incremental Health Benefits Cost of Bipolar Disorder among Insured Employees 2005 Annual Meeting New Research Abstracts May 24th, 2005
Kleinman N, Brook RA, Gardner H, Rajagopalan K, Smeeding JE. Incremental Health Benefits Cost of Bipolar Disorder among Insured Employees J Manag Care Pharm 2005 April;11(3):273-274
Kleinman N, Brook RA, Gardner H, Rajagopalan K, and Smeeding J. Incremental Health Benefits Cost of Bipolar Disorder among Insured Employees. Value Health, Nov 2005. 8(6):A237 May 17, 2005
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Incremental Sick Leave Costs and Lost Time Among Employees with Psychiatric and Medical Conditions Value Health. 2009:12(3):A87-8 May 16-20, 2009
Rajagopalan K, Kleinman NL, Brook RA, Smeeding JE, Novak S, Gardner HH. Likelihood of employment termination for employees with Bipolar Disorder treated with different psychotropic Medications (ISPOR 06 BPD Employment Termination PosterValue Health. May 2006:9(3):A73 May 22, 2006
Rajagopalan K, Kleinman NL, Brook RA, Cape A, Smeeding JE, Loebel A. Logistic Regression to Identify the Factors Predicting the Likelihood of Lurasidone Initiation in a US Employer Database. Value Health. 2013 May;16(3):a58.
Brook RA, Rajagopalan K, Novak S, Kleinman NL, Smeeding JE, Gardner HH. Lost Work Days and Emergency Department Visits among Patients Treated for Bipolar Disorder 2006 Annual Meeting New Research Abstracts p 315-316 May 24, 2006
Kleinman N, Rajagopalan K, Brook RA, Smeeding JE, Gardner H. Physical and Mental Comorbidities among Employees with Bipolar Disorder: Analysis of AHRQ 261 Specific Categories J Manag Care Pharm. 2005 April;11(3):279
Kleinman N, Rajagopalan K, Brook RA, Smeeding JE, and Gardner H. Physical and Mental Comorbidities among Employees with Bipolar Disorder: Analysis of AHRQ 261 Specific Categories 2005 Annual Meeting New Research Abstracts May 24th, 2005 s
Kleinman N, Gardner H, Rajagopalan K, Brook RA, Smeeding JE. Physical and Mental Comorbidities among Employees with Bipolar Disorder: Analysis of Major Diagnostic Categories 2005 Annual Meeting New Research Abstracts May 24th, 2005. .
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009

Cancer

Fuldeore MJ, Brook RA, Smeeding JE, Dabbous OH. Persistence with Leuprolide Acetate in patients with Prostate Cancer Value Health May 2008:11(3):A73
Brook RA, Smeeding JE, Carlisle JA.  Cancer Concerns and Oncology Care Management in the United States. Value Health 2017;20(5):A130     Click    For Poster     For Abstract
Brook RA, Smeeding JE. United States Medical and Pharmacy Director Cancer Concerns. J Manag Care Spec Pharm. 2017 Mar;23(3-a Suppl):S37     Click For Poster   For Abstract
Brook RA, McManama SH, Sax MJ, Smeeding JE. Cancer Concerns from United States Managed Care Medical and Pharmacy Directors 2016      Click   For Poster   For Abstract

Cholesterol

Brook RA, Carlisle JA, Smeeding JE. Cholesterol Management by US Health Plans. Value Health 2017;20(5):A278     Click For Poster   For Abstract
Brook RA, Smeeding JE. Current Formulary Based Cholesterol Management in the United States. J Manag Care Spec Pharm. 2017 Mar;23(3-a Suppl):S39      Click    For Poster   For Abstract
Brook RA, McManama SH, Sax MJ, Smeeding JE. Cholesterol Management in the US     Click   For Poster   For Abstract

Chronic Constipation

Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Incremental Sick Leave Costs and Lost Time Among Employees with Psychiatric and Medical Conditions Value Health. 2009:12(3):A87-8 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Baran RW. Annual Direct and Indirect Cost of Illness in Employees with Irritable Bowel Syndrome plus Constipation Am J Gastroenterol. 2008 Sep;103(S1):S381 2008 Sep
Brook RA, Talley NJ, Kleinman NK, Baran RW. Functional gastrointestinal disorder comorbidities: Comparisons of prevalence and costs in the 6 months before and after diagnoses of constipation (C) and irritable bowel syndrome and constipation (IBS+C). Am J Gastroenterol. Sep 2007; 102(suppl2):S510 Sep 2007
Kleinman NK, Brook RA, Melkonian AK, Baran RW, Talley NJ. Medical, Pharmacy, and Sick Leave Costs for Constipation and for Irritable Bowel Syndrome with Constipation in the 6 Months Before and After Diagnosis: An Employer Perspective Am J Gastroenterol. Sep 2007; 102(suppl2):S451-452 Sep 2007
Brook RA, Kleinman NL, Melkonian AK, Talley NJ, Locke, GR, Baran RW. The Prevalence and Costs to Treat Comorbidities in Persons with Constipation and Irritable Bowel Syndrome with Constipation in the 6 Months After Diagnosis: An Employer Perspective Am J Gastroenterol. 2008 Sep;103(S1):S459-460 2008 Sep
Ahn J, Talley NJ, Brook RA, Nichol MB, McCombs J, Baran RW. Constipation in a Medicaid population: Trends in prevalence, age, gender, and costs in the 12 months after diagnosis from 1997 to 2002 using a random sample of California Medicaid (Medi-Cal) data Gastroenterology (2007),:132(4),Suppl 2, A-678
Ahn J, Nichol M, Brook RA, McCombs J, Baran RW. Cost estimates of chronic constipation in California Medicaid (Medi-Cal) patients. J Manag Care Pharm. 2007. Mar;13(2):174-175
Brook RA, Talley NJ, Kleinman NK, Baran RW. Functional gastrointestinal disorder comorbidities: Comparisons of prevalence and costs in the 6 months before and after diagnoses of constipation (C) and irritable bowel syndrome and constipation (IBS+C). Am J Gastroenterol. Sep 2007; 102(suppl2):S510 Sep 2007

Comparative Data

Brook RA, Rajagoplan K, Hassan M, Young J, Smeeding J, Pikalov. Annual Direct and Indirect Costs of Employees with Bipolar Disorders, Schizophrenia, and Controls from 2001 to 2011. Academy Health. 2013 Annual Research Meeting Poster Presentations, p876-877. Poster C#1254     Click   For Poster.     For Abstract
Brook RA, Rajagopalan K, Kleinman N, Hassan M, Young J, Pikalov A. Annual Direct and Indirect Costs of US Employees with Bipolar Disorders, Schizophrenia and Controls from 2001 to 2011. 2013 Annual Meeting New Research Abstracts, Available at www.psych.org    For Poster
Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu A. Comparative Health Benefit Costs of Employees with Diabetic Macular Edema, Diabetic Retinopathy, or Diabetes Versus No Diabetes in the United States. Value Health. May 2013;16(3):A161
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44
Crawley JA, Brook R, Smeeding J. Retrospective Analysis of Switching from a Twice-Daily Proton Pump Inhibitor to Once-Daily Esomeprazole Am J Gastroenterology, October 2004:9(s10):S232 October 2004
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Velez FF,  Brook RA, Wingenbach DD, Smeeding JE.  Comparisons of the utilization, costs, and services by location of care for employees whose spouses with epilepsy have partial onset seizures and are managed by monotherapy or adjunctive therapy. Presented at the American Epilepsy Society Anual Meeting, 2015   Click for Abstract  Click for Poster

Comparative Effectiveness Research

Sax MJ, Smeeding JE, Brook RA.  The Use of Comparative Effectiveness Research and Evidence Based Medicine in US Payor Decision Making. Value Health. 2015;18:A541.   Click for Abstract    Click for Poster

Constipation

Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
Kleinman NL, Brook RA, Melkonian AK, Baran RW. Assessment of Work Absences Associated with Constipation Am J Gastroenterol. Sep 2006; 101(suppl2):S409 Sep 2006
Brook RA, Kleinman NL, Melkonian AK, Baran RW. Cost of Illness for Constipation: Medical, Pharmacy, and Work Absence Costs in Employees With or Without Constipation Am J Gastroenterol. Sep 2006; 101(suppl2):S408 Sep 2006
Kleinman NL, Brook RA, Melkonian AK, Evans S, Talley NJ, Baran RW. Direct cost similarities by point of service for persons with Constipation and Irritable Bowel Syndrome with Constipation in the 6 Months Before and After Diagnosis: An employer perspective Value Health. May 2008:11(3):A86-87. May 5, 2008
Kleinman NL, Brook RA, Melkonian AK, Baran RW. Direct costs by point of service for persons with and without constipation: An employer perspective. J Manag Care Pharm. 2007. Mar;13(2):177 2007. Mar;13
Brook RA, Talley NJ, Kleinman NK, Baran RW. Functional gastrointestinal disorder comorbidities: Comparisons of prevalence and costs in the 6 months before and after diagnoses of constipation (C) and irritable bowel syndrome and constipation (IBS+C). Am J Gastroenterol. Sep 2007; 102(suppl2):S510 Sep 2007
Kleinman NL, Brook RA, Melkonian AK, Baran RW. Healthcare Cost Comparisons by Point of Service for Persons With or Without Constipation. Am J Gastroenterol. Sep 2006; 101(suppl2):S408 Sep 2006
Kleinman NK, Brook RA, Melkonian AK, Baran RW, Talley NJ. Medical, Pharmacy, and Sick Leave Costs for Constipation and for Irritable Bowel Syndrome with Constipation in the 6 Months Before and After Diagnosis: An Employer Perspective Am J Gastroenterol. Sep 2007; 102(suppl2):S451-452 Sep 2007
Ahn J, Brook RA, Nichol MB, McCombs J, Talley NJ, Locke, GR, Baran RW. Similarities between Constipation with and without Irritable Bowel Syndrome in a Medicaid population: Costs trends by category in the 12 months after diagnosis from 1997 to 2002 using a random sample of California Medicaid (Medi-Cal) data Gastroenterology (2008), Vol. 133, No. 4 May 20, 2008
Brook RA, Kleinman NL, Melkonian AK, Talley NJ, Locke, GR, Baran RW. The Prevalence and Costs to Treat Comorbidities in Persons with Constipation and Irritable Bowel Syndrome with Constipation in the 6 Months After Diagnosis: An Employer Perspective Am J Gastroenterol. 2008 Sep;103(S1):S459-460 2008 Sep
Brook RA, Kleinman NL, Melkonian AK, Baran RW. The Prevalence and Costs to Treat GI Comorbidities in Persons with Constipation The American College of Gastroenterology Annual Scientific Meeting Am J Gastroenterol. Sep 2006; 101(suppl2):S407-8 Sep 2006
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44

COPD

York JM, Smeeding J, Brook R, Wong L, Leady M, Kagerman L, Klein G. A Retrospective Economic Comparison of Combined Ipratroprium Bromide and Albuterol versus Individual Components in Chronic Obstructive Pulmonary Disease (COPD) Patients J Manag Care Pharm. April 2005;11(3):279 (Presented 4-2005)

Depression

Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression, Ann Rheum Dis 2011;70(Suppl3):189)
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression Ann Rheum Dis 2011;70(Suppl3):189) 2011

Diabetes

Brook RA, Kleinman NL, Wingenbach D, Bron MS, Baran RW. Medication Adherence and the Direct Medical and Prescription Cost Impact of Fixed vs Loose Dose Thiazolidinedione Combination Products Among Type 2 Diabetes Patients. Presented at the Academy of Managed Care Pharmacy 20th Annual Meeting & Showcase, San Francisco, CA, Moscone West Convention Center, April 16-19, 2008. J Manag Care Pharm. Mar 2008;14(2):235-236
Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu A. Comparative Health Benefit Costs of Employees with Diabetic Macular Edema, Diabetic Retinopathy, or Diabetes Versus No Diabetes in the United States. Value Health. May 2013;16(3):A161
Brook RA, Kleinman NK, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu, A. How Does Diabetic Eye Disease Affect the American Worker? American Diabetes Association 73rd Annual Meeting (2013). Poster #618-P
Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression, Ann Rheum Dis 2011;70(Suppl3):189)
Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression. Ann Rheum Dis 2011;70(Suppl3):189)
Brook RA, Kleinman NL, Wingenbach D, Bron MS, Baran RW. Medication Adherence and the Direct Medical and Prescription Cost Impact of Fixed vs Loose Dose Thiazolidinedione Combination Products Among Type 2 Diabetes Patients. Presented at the AMCP 20th Annual Meeting & Showcase, San Francisco, CA, April 16-19, 2008. J Manag Care Pharm. Mar 2008;14(2):235-236
Brook RA, Kleinman NL, Wingenbach D, Bron MS, Pandya B, Baran RW. Medication Possession Ratio and Health Benefit Cost Comparisons in Type 2 Diabetic Patients using Fixed and Loose Dose Thiazolidinedione Combination Products. Presented at the American Diabetes Association Annual Meeting June 7-9, 2008, San Francisco, CA. Diabetes. June 2008; 57 (sup 1): a346
Brook RA, Kleinman NK, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu, A. How Does Diabetic Eye Disease Affect the American Worker? American Diabetes Association 73rd Annual Meeting (2013). Poster #618-P
Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression Ann Rheum Dis 2011;70(Suppl3):189) 2011

Diabetic Macular Edema

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu A. Comparative Health Benefit Costs of Employees with Diabetic Macular Edema, Diabetic Retinopathy, or Diabetes Versus No Diabetes in the United States. Value Health. May 2013;16(3):A161
Brook RA, Kleinman NK, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu, A. How Does Diabetic Eye Disease Affect the American Worker? American Diabetes Association 73rd Annual Meeting (2013). Poster #618-P

Diabetic Retinopathy

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu A. Comparative Health Benefit Costs of Employees with Diabetic Macular Edema, Diabetic Retinopathy, or Diabetes Versus No Diabetes in the United States. Value Health. May 2013;16(3):A161
Brook RA, Kleinman NK, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu, A. How Does Diabetic Eye Disease Affect the American Worker? American Diabetes Association 73rd Annual Meeting (2013). Poster #618-P

Diagnostic Testing

Brook RA, Smeeding JE, Carlisle JA, Sax MJ. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in US Health Plans: Results from a Survey of Medical and Pharmacy Directors. Value Health. 2016;19:A310   Click for Abstract   Click for Poster 
Brook RA, McManama SH, Sax MJ, Smeeding JE. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in the United States (US)     Click For Poster   For Abstract

EMRs/EHRs (Electronic Medical/Health Records)

Brook RA, Sax MJ, Carlisle JA, Smeeding JE. Health Plan Coverage for Medical Devices and the Use of Electronic Medical Record Systems. Value Health. 2016;19:A308.     Click for Abstract   Click for Poster

Epilepsy

Velez FF, Brook RA, Young JW. Progression to Adjunctive Therapy among Commercially-Insured Patients with Partial Onset Epilepsy. 67th Annual Meeting of the American Academy of Neurology, April 18 67th Annual Meeting of the American Academy of Neurology, April 18
Brook RA, Young JW, Smeeding JE, Velez FF. Commonly used adjunctive therapies for persons with partial­onset seizures. ASHP Summer Meeting Poster #20-M
Brook RA, Smeeding JE, Young J, Velez FF. Methodological Issues in Classifying Adjunct Anti Epileptic Drug (AED) treatment in claims data: Analysis of the effect of the minimum AED Co-administration period. Value Health 2015, 18: A290 (ISPOR)
Brook RA, Smeeding JE, Young JW, Velez FF. Comparisons of the Health Benefit Costs Among Monotherapy and Adjunctive Therapy Patients with Epilepsy and Their Employed Spouses. Presented poster session 2, #22 at the Annual Meeting of the College of Psychiatric and Neurologic Pharmacists (CPNP), April 19-22, 2015, Tampa, Florida.  Click for Poster
Velez FF, Brook RA, Young JW. Progression to Adjunctive Therapy among Commercially-Insured Patients with Partial Onset Epilepsy. 67th Annual Meeting of the American Academy of Neurology, April 18 67th Annual Meeting of the American Academy of Neurology, April 18
Velez FF,  Brook RA, Wingenbach DD, Smeeding JE.  Comparisons of the utilization, costs, and services by location of care for employees whose spouses with epilepsy have partial onset seizures and are managed by monotherapy or adjunctive therapy. Presented at the American Epilepsy Society Anual Meeting, 2015   Click for Abstract  Click for Poster

Formulary

Brook RA, Smeeding JE. The 2015 US Payor Landscape: Results from a Survey of Medical and Pharmacy Directors on Formulary Management. Value Health. 2015;18:A528.Value Health. 2015;18:A528   Click for Abstract    Click for Poster
Smeeding JE, Sax MJ, Carlisle JA, Brook RA. Observations from U.S. Payors Today and Predictions for the Future. Value Health. 2016;19:A269.      Click for Abstract     Click for Poster
Brook RA, Carlisle JA, Smeeding JE. The 2017 US Payor Landscape: Trends and Results from Surveys of Medical and Pharmacy Directors on Formulary Management. Value Health 2017;20(5):A26     Click   For Poster   For Abstract   
Brook RA, Smeeding JE. Current Formulary Based Cholesterol Management in the United States. J Manag Care Spec Pharm. 2017 Mar;23(3-a Suppl):S39      Click    For Poster   For Abstract

Functional Dyspepsia

Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
George S, Kleinman N, Brook R, Smeeding J. Costs of Functional Dyspepsia—Results from a large US Employer Database Value Health. Nov/Dec 2006. 9(6):A189-90. November/December 2006
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
George S, Kleinman NL, Brook RA, Smeeding JE. Impact of the ROME II criteria - assessment of related comorbid prevalence and costs of patients with functional dyspepsia Gastroenterology. April 2006;130(suppl2):P-314 Abstract W1062 April 2006
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Incremental Sick Leave Costs and Lost Time Among Employees with Psychiatric and Medical Conditions Value Health. 2009:12(3):A87-8 May 16-20, 2009,
Brook RA, Talley NJ, Choung RS, Melkonian AK, Smeeding J, Kleinman NL. Prevalence, Costs and Services of Comorbid conditions associated with Functional Dyspepsia Value Health 2010;13:A71 2010
Brook RA, Talley NJ, Choung RS, Smeeding JE, Kleinman NL. The Likelihood of Having Functional Dyspepsia Based on Other Comorbid Conditions Value Health 2011:14(3):A180 2011
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009

Genetic Testing

Brook RA, Smeeding JE, Carlisle JA, Sax MJ. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in US Health Plans: Results from a Survey of Medical and Pharmacy Directors. Value Health. 2016;19:A310   Click for Abstract   Click for Poster 
Brook RA, McManama SH, Sax MJ, Smeeding JE. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in the United States (US)     Click For Poster   For Abstract

GERD

Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44
Wallander M, Wahlqvist P, Kleinman NL, Campbell S, Talley NJ, Brook RA. Comorbidities during the year following diagnosis for persons with and without GERD using the Agency for Health Research and Quality (AHRQ) 261 Specific Categories Value Health. May 2007:10(3):A147 May 22, 2007
Brook RA, Campbell S, Wahlqvist P, Wallander M, Kleinman NL, Wiklund I, Smeeding JE. Cost of illness of Gastroesophageal Reflux Disease (GERD): Comparison of medical, pharmacy, sick leave, short- and long-term disability, and workers’ compensation claims and medical claims by place of service between employees with and without GERD Gastroenterology. April 2006;130(suppl2):A-27 May 21, 2006
Brook RA, Campbell S, Wahlqvist P, Wallander M, Kleinman NL, Wiklund I, Smeeding, JE. Cost of illness to the employer of Gastroesophageal Reflux Disease (GERD): Comparison of medical, pharmacy, sick leave, short- and long-term disability, and workers’ compensation claims and medical claims by place of service between employees with and without GERD. Value Health  May 22, 2006:9(3):A46
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Incremental Sick Leave Costs and Lost Time Among Employees with Psychiatric and Medical Conditions Value Health. 2009:12(3):A87-8 May 16-20, 2009
Wahlqvist P, Brook RA, Campbell S, Wallander M, Kleinman NL, Wiklund I, Smeeding JE. Objective measurement of hourly and annual productivity while at work in employees with Gastroesophageal Reflux Disease (GERD) compared with employees without GERD Gastroenterology. April 2006;130(suppl2):A-453 May 23, 2006.
Wahlqvist P, Brook RA, Campbell S, Wallander M, Wiklund I, Kleinman NL, Smeeding JE. Objective Measurement of Productivity While at Work in US Employees with and without Gastroesophageal Reflux Disease (GERD) Value Health. May 2006:9(3):A49 May 22, 2006
Crawley JA, Brook R, Smeeding J. Retrospective Analysis of Switching from a Twice-Daily Proton Pump Inhibitor to Once-Daily Esomeprazole Am J Gastroenterology, October 2004:9(s10):S232 October 2004
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Smeeding JE, Joshua-Gotlib S, Warner D. Comparison of the Medication Possession Ratio Alone and in Combination with Breakthrough Events for Classifying Patients with Acid-Related Diseases Value Health. May 2005:8(3):373

Gout

Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Novak S, Patel PA, Kleinman NL, Brook RA, Melkonian AK, Smeeding JE, Joseph-Ridge N. A comparison of average annual medical services for comorbid conditions associated with metabolic syndrome found in employees with gout versus those without gout J Manag Care Pharm. 2006. Mar;12(2):173 April 7, 2006
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Kleinman NL, Brook RA, Patel PA, Melkonian AK, Smeeding JE, Joseph-Ridge N. Cost comparisons by place of service for persons with and without gout. (ASHP) Mid-Year Meeting, Poster #438. December 2005
Kleinman NL, Patel PA, Brook RA, Melkonian AK, Smeeding JE, Joseph-Ridge N. Economic Burden of Gout to the Employer J Manag Care Pharm. 2005. Sep;11(7):601 October 7, 2005
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Kleinman NL, Patel PA, Brook RA, Melkonian AK, Smeeding JE, Joseph-Ridge N. Lost Days and Productivity Impact of Gout (ACR) / ARHP Annual Scientific Meeting in San Diego, California, Program Number: (548) 1772 November 16, 2005, San Diego, CA

Hepatitis-C

Brook RA, Kleinman NL, Smeeding JE. Comparison of Direct Medical Costs an Services by Point of Service and Prescription Cost for Persons With Hepatitis-C With and Without Treatment. Value Health 2011:14(3):A181
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44
Su J, Kleinman NL, Brook RA, Melkonian AK, Smeeding JE, Corey-Lisle P. The Impact of Hepatitis-C Viral (HCV) Treatment on Work Absence and Productivity Gastroenterology. May 2009:16(5) Suppl, M1810.
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Baran RW, Brook RA, Kleinman NL, Beren IA, Dietz B. Employees Living with Human Immunodeficiency Virus (HIV): Impact of Disease and Antiretroviral Therapies on Healthcare Costs and Productivity J Manag Care Pharm. March 2012; 18(2):174.
Baran R, Samp J, Walker D, Brook R, Kleinman N, Young J, Smeeding J. The Direct and Indirect Costs of Employees with Hepatitis C Vary by Stage of Disease. Presented at Academy Health’s 2014 Annual Research Meeting Presented at Academy Health’s 2014 Annual Research Meeting, Session C, #963, San Diego, California June 8–10, 2014
Su J, Kleinman NL, Brook RA, Melkonian AK, Smeeding JE, Corey-Lisle P. The Impact of Hepatitis-C Viral (HCV) Treatment on Work Absence and Productivity Gastroenterology. May 2009:16(5) Suppl, M1810.
Brook RA, Kleinman NL, Su J, Corey-Lisle PK, Iloeje UH. Absenteeism and Productivity Among Employees Being Treated for Hepatitis C Am J Manag Care. October 2011;17(10):657-664.
Su J, Brook RA, Kleinman NL, Corey-Lisle P. The Impact of Hepatitis-C Viral (HCV) Infection on Work Absence, Productivity, and Healthcare Benefit Costs Hepatology. 2010;52:436-442. 2010

HIV

Baran RW, Brook RA, Kleinman NL, Beren IA, Dietz B. Employees Living with Human Immunodeficiency Virus (HIV): Impact of Disease and Antiretroviral Therapies on Healthcare Costs and Productivity J Manag Care Pharm. March 2012; 18(2):174.
Su J, Kleinman NL, Brook RA, Melkonian AK, Smeeding JE, Corey-Lisle P. The Impact of Hepatitis-C Viral (HCV) Treatment on Work Absence and Productivity Gastroenterology. May 2009:16(5) Suppl, M1810.

Insomnia And Sleep Disorders

Brook RA, Kleinman NL, Smeeding JE. Cost, Absences, Prevalence and Impact of Bipolar Disorder, Other Mental Disorders, Chronic Constipation, Functional Dyspepsia, Gastroesophageal Reflux Disease, Gout, And Insomnia. J Manag Care Pharm September 2011; 17(7):556
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44
Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Kleinman NL, Brook RA, Melkonian AK, Doan JF, Baran RW. Assessment of Work Absences Associated with Insomnia J Manag Care Pharm. Sep 2007;13(8):690 October 26, 2007
Brook RA, Kleinman NL, Melkonian AK, Doan JF, Baran RW. Cost of illness for insomnia: medical, pharmacy, and work absence costs in employees with or without insomnia Sleep 2007; 30(suppl):A246 2007
Brook RA, Kleinman NL, Melkonian AK, Doan JF, Baran RW. Healthcare Cost Comparisons by Point-of-Service for Employees with or without Insomnia J Manag Care Pharm. Sep 2007:13(8):701 October 26, 2007
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Incremental Sick Leave Costs and Lost Time Among Employees with Psychiatric and Medical Conditions Value Health. 2009:12(3):A87-8 May 16-20, 2009
Insomnia Research Presented at SLEEP2007: APSS: Extra Health Cost of Insomnia Reaches $3,200 an Employee 2007
Doan JF, Brook RA, Kleinman NL, Melkonian AK, Smeeding JE, Baran RW. Objective Costs and Prevalence of Comorbidities for Persons with and without Insomnia Value Health Nov/Dec 2007. 10(6): A384-385 October 22, 2007

Irritable Bowel Syndrome

Brook RA, Talley NJ, Kleinman NK, Baran RW. Functional gastrointestinal disorder comorbidities: Comparisons of prevalence and costs in the 6 months before and after diagnoses of constipation (C) and irritable bowel syndrome and constipation (IBS+C). Am J Gastroenterol. Sep 2007; 102(suppl2):S510 Sep 2007
Kleinman NK, Brook RA, Melkonian AK, Baran RW, Talley NJ. Medical, Pharmacy, and Sick Leave Costs for Constipation and for Irritable Bowel Syndrome with Constipation in the 6 Months Before and After Diagnosis: An Employer Perspective Am J Gastroenterol. Sep 2007; 102(suppl2):S451-452 Sep 2007
Brook RA, Kleinman NL, Melkonian AK, Baran RW. Annual Direct and Indirect Cost of Illness in Employees with Irritable Bowel Syndrome plus Constipation Am J Gastroenterol. 2008 Sep;103(S1):S381 2008 Sep
Kleinman NL, Brook RA, Melkonian AK, Evans S, Talley NJ, Baran RW. Direct cost similarities by point of service for persons with Constipation and Irritable Bowel Syndrome with Constipation in the 6 Months Before and After Diagnosis: An employer perspective Value Health. May 2008:11(3):A86-87. May 5, 2008
Brook RA, Talley NJ, Kleinman NK, Baran RW. Functional gastrointestinal disorder comorbidities: Comparisons of prevalence and costs in the 6 months before and after diagnoses of constipation (C) and irritable bowel syndrome and constipation (IBS+C). Am J Gastroenterol. Sep 2007; 102(suppl2):S510 Sep 2007
Kleinman NK, Brook RA, Melkonian AK, Baran RW, Talley NJ. Medical, Pharmacy, and Sick Leave Costs for Constipation and for Irritable Bowel Syndrome with Constipation in the 6 Months Before and After Diagnosis: An Employer Perspective Am J Gastroenterol. Sep 2007; 102(suppl2):S451-452 Sep 2007
Ahn J, Brook RA, Nichol MB, McCombs J, Talley NJ, Locke, GR, Baran RW. Similarities between Constipation with and without Irritable Bowel Syndrome in a Medicaid population: Costs trends by category in the 12 months after diagnosis from 1997 to 2002 using a random sample of California Medicaid (Medi-Cal) data Gastroenterology (2008), Vol. 133, No. 4 May 20, 2008
Brook RA, Kleinman NL, Melkonian AK, Talley NJ, Locke, GR, Baran RW. The Prevalence and Costs to Treat Comorbidities in Persons with Constipation and Irritable Bowel Syndrome with Constipation in the 6 Months After Diagnosis: An Employer Perspective Am J Gastroenterol. 2008 Sep;103(S1):S459-460 2008 Sep

IVR Systems

Brook RA, Smeeding JE, Sachse SL, Cook J, Novak S. Multilingual Interactive Voice Response System for Patient Reported Outcomes in Multiple Countries AMAI Clinical Trials Expo 2005 October 24, 2005

Medicaid

Ahn J, Talley NJ, Brook RA, Nichol MB, McCombs J, Baran RW. Constipation in a Medicaid population: Trends in prevalence, age, gender, and costs in the 12 months after diagnosis from 1997 to 2002 using a random sample of California Medicaid (Medi-Cal) data Gastroenterology (2007),:132(4),Suppl 2, A-678
Ahn J, Nichol M, Brook RA, McCombs J, Baran RW. Cost estimates of chronic constipation in California Medicaid (Medi-Cal) patients. J Manag Care Pharm. 2007. Mar;13(2):174-175
Ahn J, Brook RA, Nichol MB, McCombs J, Talley NJ, Locke, GR, Baran RW. Similarities between Constipation with and without Irritable Bowel Syndrome in a Medicaid population: Costs trends by category in the 12 months after diagnosis from 1997 to 2002 using a random sample of California Medicaid (Medi-Cal) data Gastroenterology (2008), Vol. 133, No. 4 May 20, 2008

Medical Devices

Brook RA, Sax MJ, Carlisle JA, Smeeding JE. Health Plan Coverage for Medical Devices and the Use of Electronic Medical Record Systems. Value Health. 2016;19:A308.     Click for Abstract   Click for Poster

Methodology

Brook RA, Smeeding JE, Joshua-Gotlib S, Warner D. Comparison of the Medication Possession Ratio Alone and in Combination with Breakthrough Events for Classifying Patients with Acid-Related Diseases Value Health. May 2005:8(3):373
Brook RA, Smeeding JE, Young J, Velez FF. Methodological Issues in Classifying Adjunct Anti Epileptic Drug (AED) treatment in claims data: Analysis of the effect of the minimum AED Co-administration period. Value Health 2015, 18: A290 (ISPOR)

Multiple Sclerosis

Brook RA, Rajagopalan K, Kleinman NL, Beren I. Direct Medical Costs and the Likelihood of Health Service Utilization Before and After Initiation of Avonex (Interferon β1a IM) Treatment Among Persons with Multiple Sclerosis (MS) CMSC Scientific Abstract Listing 2009 CMSC:S111, page 149.
Kleinman NL, Brook RA, Rajagopalan K, Melkonian AK. Absenteeism (lost time) Among Employees with Multiple Sclerosis J Manag Care Pharm March 2008;14(2):205-206
Brook RA, Rajagopalan K, Kleinman NL, Beren I. Direct Medical Costs and the Likelihood of Health Service Utilization Before and After Initiation of Avonex (Interferon β1a IM) Treatment Among Persons with Multiple Sclerosis (MS). Value Health. 2009:12(3):A193.
Kleinman NL, Rajagopalan K. Brook RA, Melkonian AK. Health Benefit Costs Among Employees With Multiple Sclerosis. Int J of MS Care. May 2008; 10(Supp 1): 20-21.
Brook RA, Rajagopalan K, Kleinman NL, Beren IA. Medication adherence with Disease modifying treatments for multiple sclerosis: Findings from a US National database of employees. Value Health 2009;13:A371
Brook RA, Rajagopalan K, Kleinman NL, Melkonian AK. Prevalence and Costs of Comorbidities Among Persons with and without Multiple Sclerosis: An Analysis of the AHRQ Major and Specific Diagnostic Categories Value Health. May 2008:11(3):A136.
Kleinman NL, Rajagopalan K, Brook RA, Melkonian AK. Severity of Illness Among Persons with Multiple Sclerosis: An Analysis of Cost Quintiles. Value Health. May 2008:11(3):A141-142
Brook RA, Kleinman NL, Rajagopalan K, Melkonian AK. The Impact of Multiple Sclerosis On Absenteeism Int J of MS Care. May 2008; 10(Supp 1): 11.

Ophthalmic Study

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Miller B, Turpcu A. Comparative Health Benefit Costs of Employees with Diabetic Macular Edema, Diabetic Retinopathy, or Diabetes Versus No Diabetes in the United States. Value Health. May 2013;16(3):A161

Payors / Payers

Brook RA, Sax MJ, Smeeding JE. The 2015 US Payor Landscape for Specialty Pharmacy: Results from a Survey of Medical and Pharmacy Directors. Presented at the 3rd Annual Meeting of the National Association of Specialty Pharmacy, National Harbor, MD, September 30-October 1st, 2015. (NASP)  Click for Poster
Sax MJ, Smeeding JE, Brook RA.  The Use of Comparative Effectiveness Research and Evidence Based Medicine in US Payor Decision Making. Value Health. 2015;18:A541.   Click for Abstract    Click for Poster
Brook RA, Smeeding JE, Sax MJ. The United States Specialty Pharmacy Payor Landscape. Value Health. 2015;18:A528 Click for Abstract    Click for Poster
Brook RA, Smeeding JE, Carlisle JE, Sax MJ.  The US Payor Landscape for Specialty Pharmacy: Results from a Survey of Medical and Pharmacy Directors. J Manag Care Spec Pharm. 2016 Apr;22 (4-a):S117.  Click for poster  Click for Abstract
Smeeding JE, Sax MJ, Carlisle JA, Brook RA. Observations from U.S. Payors Today and Predictions for the Future. Value Health. 2016;19:A269.      Click for Abstract     Click for Poster
Brook RA, Carlisle JA, Smeeding JE. The 2017 US Payor Landscape: Trends and Results from Surveys of Medical and Pharmacy Directors on Formulary Management. Value Health 2017;20(5):A26     Click   For Poster   For Abstract   
Brook RA, Smeeding JE. The US Payor Landscape: Results from a Survey of Medical and Pharmacy Directors on Formulary Management. J Manag Care Spec Pharm. 2017 Mar;23(3-a Suppl):S105      Click    For Poster   For Abstract   

Pulmonology

York JM, Smeeding J, Brook R, Wong L, Leady M, Kagerman L, Klein G. A Retrospective Economic Comparison of Combined Ipratroprium Bromide and Albuterol versus Individual Components in Chronic Obstructive Pulmonary Disease (COPD) Patients J Manag Care Pharm. April 2005;11(3):279 (Presented 4-2005)
Marsh W, Smeeding J, York J, Sekar K, Ramanthan R. Cost-minimization Analysis of Treatment for Respiratory Distress Syndrome American Society for Health Systems Pharmacists, Mid-Year Meeting, 2003
Marsh W, Smeeding J, York J, Ramanthan R, Sekar K. Cost-minimization Analysis of Two Surfactant Treatments for Respiratory Distress Syndrome ASHP 2004 Poster Surfactant
Kleinman NL, Brook RA, Ramachandran S, Wagner S. Pediatric Asthma: An Employer Perspective on Annual Employee and Dependent Costs for Medical Care and Prescription Drugs Value Health May 2008:11(3):A273. May 6, 2008

Quintile Analysis

Brook RA, Kleinman NL, Smeeding JE, et al. The Use of Quintile Analysis as a Measure of Disease Severity: A Comparison Within and Across Diseases Value Health. May 2006:9(3):A58 May 22, 2006

Respiratory Distress Syndrome

Marsh W, Smeeding J, York J, Sekar K, Ramanthan R. Cost-minimization Analysis of Treatment for Respiratory Distress Syndrome American Society for Health Systems Pharmacists, Mid-Year Meeting, 2003
Marsh W, Smeeding J, York J, Ramanthan R, Sekar K. Cost-minimization Analysis of Two Surfactant Treatments for Respiratory Distress Syndrome ASHP 2004 Poster Surfactant

Rheumatoid Arthritis

Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression, Ann Rheum Dis 2011;70(Suppl3):189)
Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression Ann Rheum Dis 2011;70(Suppl3):189) 2011
Brook RA, Roy S, Kleinman NL, Cifaldi MA. Impact of Rheumatoid Arthritis on Health Care Costs and Work Productivity: A Comparative Assessment With Diabetes and Depression. Ann Rheum Dis 2011;70(Suppl3):189)

Schizophrenia

Brook RA, Rajagoplan K, Hassan M, Young J, Smeeding J, Pikalov. Annual Direct and Indirect Costs of Employees with Bipolar Disorders, Schizophrenia, and Controls from 2001 to 2011. Academy Health. 2013 Annual Research Meeting Poster Presentations, p876-877. Poster C#1254     Click   For Poster.     For Abstract
Brook RA, Rajagopalan K, Kleinman N, Hassan M, Young J, Pikalov A. Annual Direct and Indirect Costs of US Employees with Bipolar Disorders, Schizophrenia and Controls from 2001 to 2011. 2013 Annual Meeting New Research Abstracts, Available at www.psych.org    For Poster
Brook RA, Rajagopalan K, Kleinman NL, Hassan M, Young JW, Smeeding JE, Pikalov A. Direct and Indirect Costs Among US Employees with and without Bipolar Disorder or Schizophrenia: Annual Cost Trends from 2001 to 2011. Value Health. 2013 May;16(3): A59

Specialty Drugs

Brook RA, Smeeding JE, Carlisle JA.  The Management of Specialty Drugs, Specialty Pharmacies and Biosimilar Drugs in the United States. Value Health2017;20(5):A26     Click    For Poster   For Abstract

Specialty Pharmaceuticals

Specialty Pharmacy

Brook RA, Sax MJ, Smeeding JE. The 2015 US Payor Landscape for Specialty Pharmacy: Results from a Survey of Medical and Pharmacy Directors. Presented at the 3rd Annual Meeting of the National Association of Specialty Pharmacy, National Harbor, MD, September 30-October 1st, 2015. (NASP)  Click for Poster
Brook RA, Smeeding JE, Sax MJ. The United States Specialty Pharmacy Payor Landscape. Value Health. 2015;18:A528 Click for Abstract    Click for Poster
Brook RA, Smeeding JE, Carlisle JA, Sax MJ. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in US Health Plans: Results from a Survey of Medical and Pharmacy Directors. Value Health. 2016;19:A310   Click for Abstract   Click for Poster 
Brook RA, Smeeding JE, Carlisle JA.  The Management of Specialty Drugs, Specialty Pharmacies and Biosimilar Drugs in the United States. Value Health2017;20(5):A26     Click    For Poster   For Abstract
Brook RA, McManama SH, Sax MJ, Smeeding JE. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in the United States (US)     Click For Poster   For Abstract

Virology

Brook RA, Kleinman NL, Smeeding JE. Comparison of Direct Medical Costs an Services by Point of Service and Prescription Cost for Persons With Hepatitis-C With and Without Treatment. Value Health 2011:14(3):A181
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers' Compensation Costs and Absence Days Using a National Database. Value Health 2010;13(3):A90
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Employee Workers’ Compensation Costs and Absence Days Using a National Database. J Manag Care Pharm. March 2010; 16(2):145-6
Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Comparisons of Relative Risks of Serious Comorbidities Among Employees with and without Insomnia, GERD, Hepatitis C, Multiple Sclerosis and Chronic Constipation. Value Health May 2008:11(3):A44
Baran RW, Brook RA, Kleinman NL, Beren IA, Dietz B. Employees Living with Human Immunodeficiency Virus (HIV): Impact of Disease and Antiretroviral Therapies on Healthcare Costs and Productivity J Manag Care Pharm. March 2012; 18(2):174.
Su J, Kleinman NL, Brook RA, Melkonian AK, Smeeding JE, Corey-Lisle P. The Impact of Hepatitis-C Viral (HCV) Treatment on Work Absence and Productivity Gastroenterology. May 2009:16(5) Suppl, M1810.

Manuscripts

ARD

Asthma

Kleinman NL, Ramachandran S, Brook RA. Health Benefit Cost of Employees with Children with Asthma Ann Allergy Asthma Immunol. August 2009;103:114–120

Bipolar Disorder

Rajagopalan K, Kleinman NL, Brook RA, Gardner HH, Brizee TJ, Smeeding JE. Costs of physical and mental comorbidities among employees: a comparison of those with and without bipolar disorder Curr Med Res Opin. 2006 Mar;22(3):443-52
Brook RA, Kleinman NL, Rajagopalan K. Employee costs before and after treatment initiation for bipolar disorder Am J Manag Care. 2007 Apr;13(4):179-86
Brook RA, Rajagopalan K, Kleinman NL, Smeeding JE, Brizee TA; Gardner HH. Incurring Greater Health Care Costs: Risk Stratification of Bipolar Disorder Employees
Kleinman NL, Brook RA, Rajagopalan K, Gardner HH, Brizee TJ, Smeeding JE. Lost time, absence costs, and reduced productivity output for employees with bipolar disorder J Occup Environ Med 2005 Nov;47(11):1117-24
Gardner HH, Kleinman NL, Brook RA, Rajagopalan K, Brizee TJ, Smeeding JE. The economic impact of bipolar disorder in an employed population from an employer perspective J Clin Psychiatry 2006 Aug;67(8):1209-18

COPD

York JM, Smeeding J, Brook RA, Hoehler F, Klein GL. Exploratory Economic Evaluation of Patients With COPD on a Combination Product Versus Individual Components (Ipratropium Bromide and Albuterol) Adv Ther. 2007 Jul-Aug;24(4):757-771 2007

Diabetes

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Turpcu A. United States comparative costs and absenteeism of diabetic ophthalmic conditions. Postgrad Med. 2014 Dec 31:1-8. [Epub ahead of print]

Diabetic Macular Edema

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Turpcu A. United States comparative costs and absenteeism of diabetic ophthalmic conditions. Postgrad Med. 2014 Dec 31:1-8. [Epub ahead of print]

Diabetic Retinopathy

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Turpcu A. United States comparative costs and absenteeism of diabetic ophthalmic conditions. Postgrad Med. 2014 Dec 31:1-8. [Epub ahead of print]

ESRD

Pai AB, Smeeding JE, Brook RA. The role of sevelamer in achieving the kidney disease outcomes quality initiative (K/DOQI) guidelines for hyperphosphatemia Curr Med Res Opin. 2004 Jul;20(7):991-9

Functional Dyspepsia

Brook RA, Kleinman NL, Choung RS, Smeeding JE, Talley NJ. Excess Comorbidity Prevalence and Cost Associated with Functional Dyspepsia in an Employed Population Dig Dis Sci 2012. 57(1):109–118. Epub 2011 Jul 13.
Brook RA, Kleinman NL, Choung RS, Melkonian AK, Smeeding JE, Talley NJ. Functional Dyspepsia Impacts Absenteeism and Direct and Indirect Costs Clin Gastroenterol Hepatol. 2010 Jun;8(6):498-503

GERD

Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Brook RA, Wahlqvist P, Kleinman NL, Wallander M-A, Campbell SM, Smeeding JE. Cost of gastro-oesophageal reflux disease to the employer: a US perspective Aliment Pharmacol Ther. 2007. 26(6):889-898
Wahlqvist P, Kleinman NL, Brook RA, Wallander M-A, Campbell SM, Smeeding JE. Objective measurement of work absence and on-the-job productivity: a case-control study of US employees with and without gastroesophageal reflux disease J Occup Environ Med. 2008;50:25-31. 2008

Good Research Practices

Hay JW, Smeeding J, Carroll NV, Drummond M, Garrison LP, Mansley EC, Mullins CD, Mycka JM, Seal B, Shi Lv. Good research practices for measuring drug costs in cost effectiveness analyses Value Health 2010 Jan-Feb;13(1):3-7
Mycka JM, Dellamano R, Kolassa EM, Wonder M, Ghosh S, Hay JW, Smeeding J. Good research practices for measuring drug costs in cost effectiveness analyses: an industry perspective Value Health. 2010 Jan-Feb;13(1):25-7
Garrison LP Jr, Mansley EC, Abbott TA 3rd, Bresnahan BW, Hay JW, Smeeding J. Good research practices for measuring drug costs in cost-effectiveness analyses Value Health 2010 Jan-Feb;13(1):8-13
Mansley EC, Carroll NV, Chen KS, Shah ND, Piech CT, Hay JW, Smeeding J. Good research practices for measuring drug costs in cost-effectiveness analyses: a managed care perspective Value Health. 2010 Jan-Feb;13(1):14-7
Shi L, Hodges M, Drummond M, Ahn J, Li SC, Hu S, Augustovski F, Hay JW, Smeeding J. Good research practices for measuring drug costs in cost-effectiveness analyses: an international perspective Value Health. 2010 Jan-Feb;13(1):28-33
Mullins CD, Seal B, Seoane-Vazquez E, Sankaranarayanan J, Asche CV, Jayadevappa R, Lee WC, Romanus DK, Wang J, Hay JW, Smeeding J. Good research practices for measuring drug costs in cost-effectiveness analyses: Medicare, Medicaid and other US government payers perspectives Value Health. 2010 Jan-Feb;13(1):18-24

Gout

Brook RA, Kleinman NL, Melkonian AK, Smeeding JE. Hourly and Annual Objective Productivity (Presenteeism) Across Several Diseases: Bipolar Disorders, Chronic Constipation, Functional Dyspepsia, GERD, Gout, and Insomnia Value Health. 2009: 12(3):A169-70 May 16-20, 2009
Novak S, Melkonian AK, Patel PA, Kleinman NL, Joseph-Ridge N, Brook RA. Metabolic syndrome-related conditions among people with and without gout: prevalence and resource use Curr Med Res Opin. 2007 Mar;23(3):623-30
Brook RA, Forsythe A, Smeeding JE, Edwards NL. Chronic gout: epidemiology, disease progression, treatment and disease burden Curr Med Res Opin. 2010: 26(12): 2813–2821 2010
Kleinman NL, Brook RA, Patel PA, Melkonian AK, Smeeding JE, Joseph-Ridge N. Lost time and Reduced Productivity Associated with Gout Value Health 2007 Jul-Aug;10(4):231-7
Brook RA, Kleinman NL, Patel PA, Melkonian AK, Brizee TJ, Smeeding JE, Joseph-Ridge N. The economic burden of gout on an employed population Curr Med Res Opin. 2006 Jul;22(7):1381-9

Hepatitis-C

Baran RW, Samp JC, Walker DR, Smeeding JE, Young JW, Kleinman NL, Brook RA.Costs and absence of HCV-infected employees by disease stage. J Med Econ. 2015 Sep;18(9):691-703. doi: 10.3111/13696998.2015.1045423. Epub 2015 Jun 11.

Insomnia And Sleep Disorders

Kleinman NL, Brook RA, Melkonian AK, Doan JF, Baran RW. Health Benefit Costs and Absenteeism due to Insomnia from the Employer’s Perspective J Clin Psychiatry 2009;70(8):1098-1104

Irritable Bowel Syndrome

Brook RA, Talley NJ, Kleinman NK, Baran RW. Functional gastrointestinal disorder comorbidities: Comparisons of prevalence and costs in the 6 months before and after diagnoses of constipation (C) and irritable bowel syndrome and constipation (IBS+C). Am J Gastroenterol. Sep 2007; 102(suppl2):S510 Sep 2007

Multiple Sclerosis

Brook RA, Rajagopalan K, Kleinman NL, Melkonian AK. Absenteeism and Health Benefit Costs Among Employees with Multiple Sclerosis Curr Med Res Opin. June 2009;25(6):1469–76.
Rajagopalan K, Brook RA, Beren IA, Kleinman NL. Comparing costs and absences for Multiple Sclerosis among US employees: pre- and post-treatment initiation Curr Med Res Opin. 2011 Jan;27(1):179–188.
Kleinman NL, Beren IA, Rajagopalan K, Brook RA. Medication adherence with disease modifying treatments for multiple sclerosis among US employees J Med Econ. 2010 Oct 19. 13(4):633-640

Ophthalmology

Brook RA, Kleinman NL, Patel S, Smeeding JE, Beren IA, Turpcu A. United States comparative costs and absenteeism of diabetic ophthalmic conditions. Postgrad Med. 2014 Dec 31:1-8. [Epub ahead of print]

Pulmonology

York JM, Smeeding J, Brook RA, Hoehler F, Klein GL. Exploratory Economic Evaluation of Patients With COPD on a Combination Product Versus Individual Components (Ipratropium Bromide and Albuterol) Adv Ther. 2007 Jul-Aug;24(4):757-771 2007
Kleinman NL, Ramachandran S, Brook RA. Health Benefit Cost of Employees with Children with Asthma Ann Allergy Asthma Immunol. August 2009;103:114–120

Rheumatoid Arthritis

Kleinman NL, Cifaldi MA, Smeeding JE, Shaw JW, Brook RA. Annual Incremental Health Benefit Costs and Absenteeism Among Employees with and Without Rheumatoid Arthritis J Occup Environ Med March 2013; 55(3):240-244. 

Rheumatology: Gout and Rheumatoid Arthritis

Brook RA, Kleinman NL, Patel PA, Melkonian AK, Brizee TJ, Smeeding JE, Joseph-Ridge N. The economic burden of gout on an employed population. Curr Med Res Opin. 2006 Jul;22(7):1381-9

Specialty Pharmaceuticals

Baran RW, Samp JC, Walker DR, Smeeding JE, Young JW, Kleinman NL, Brook RA.Costs and absence of HCV-infected employees by disease stage. J Med Econ. 2015 Sep;18(9):691-703. doi: 10.3111/13696998.2015.1045423. Epub 2015 Jun 11.
Brook RA, Smeeding JE, Carlisle JE, Sax MJ.  The US Payor Landscape for Specialty Pharmacy: Results from a Survey of Medical and Pharmacy Directors. J Manag Care Spec Pharm. 2016 Apr;22 (4-a):S117.  Click for poster  Click for Abstract
Brook RA, Smeeding JE, Carlisle JA, Sax MJ. Specialty Pharmacy, Diagnostic and Genetic Testing Coverage in US Health Plans: Results from a Survey of Medical and Pharmacy Directors. Value Health. 2016;19:A310   Click for Abstract   Click for Poster 

Virology

Brook RA, Kleinman NL, Su J, Corey-Lisle PK, Iloeje UH. Absenteeism and Productivity Among Employees Being Treated for Hepatitis C Am J Manag Care. October 2011;17(10):657-664.
Su J, Brook RA, Kleinman NL, Corey-Lisle P. The Impact of Hepatitis-C Viral (HCV) Infection on Work Absence, Productivity, and Healthcare Benefit Costs Hepatology. 2010;52:436-442. 2010
Baran RW, Samp JC, Walker DR, Smeeding JE, Young JW, Kleinman NL, Brook RA.Costs and absence of HCV-infected employees by disease stage. J Med Econ. 2015 Sep;18(9):691-703. doi: 10.3111/13696998.2015.1045423. Epub 2015 Jun 11.

Women's Health

Fuldeore MJ, Marx SE, Chwalisz K, Smeeding JE, Brook RA. Add-back therapy use and its impact on LA persistence in patients with endometriosis Curr Med Res Opin. 2010 Mar;26(3):729-36.